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Toxicology Celebrates 50 Years

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zebrafish

Zebrafish at the Sinnhuber Aquatic Research Laboratory

Upcoming Events

  • EMT FAll Picnic - September 25, 2014 at the Rotary Shelter, Willamette Park (Brand New Location)
  • EMT Research Day 2015 - January 9, 2015

Recent Department Events

  • softball tileIntoxicologist Softball Team - The team is composed of EMT, OSU, and other local friends of the gradute students and employees on the team.
  • Runnin' on EMT - Congratulations to the EMT Runnin' on EMT racing team for placing 51 out of 101 teams in the "Barrel to Keg Race to End Poverty" relay. Seventy miles from Philomath to Newport in 10 hours and 15 minutes.
  • TeamTox Retreat - TeamTox hosted the first EMT departmental graduate student and postdoc retreat on October 25, 2013, at South Beach State park.  This event was held in response to growing student requests for more opportunities to engage in department wide team building, especially between off campus and main campus laboratories.

Sudakin Farewell

Dan Sudakin leaves EMT for private practice.

Dr. Dan Sudakin left OSU and EMT to pursue his private practice in addiction medicine. Dan will remain as a courtesy faculty member for the department.

Anderson lab

Anderson Lab Passive Sampling Wristbands

A recent field study in Ohio resulted in a number of articles highlighting the work of the Anderson lab's work using silicon wristbands to measure exposure to environmental chemicals.

Articles have appeared in the NIEHS Environmental Factor, Chemical & Engineering News, Chromotography Online, Environmental Health NewsUK Chemical Watch, and, more locally, the Corvallis Gazette-Times.

 

Dashwwod Farewell

 

 

Recent Accomplishments

SRP Trainees visit UC Davis for Picnic Day

The UC Davis superfund Research Center recently invited EMT trainees to attend UC Davis Picnic Day to display posters and participate in outreach activites. Picnic Day is an annual open house event that typically draws more than 50,000 visitors to campus to learn about research.

Dr. Craig Marcus, Training Core Leader, attended with Erin Madeen (Project 1) and Andrea Knecht (Project 3).

UC Davis covereage of the event can be read here.

EHSC Profile - Joey Pryor

Environmental Health Sciences Center recently profiled Joey Pryor, a senior undergraduate student in Stacey Harper's lab. The entire article is available here.

Amy Jahr URISC Award

Amy Jahr has been awarded an Undergraduate Research, Innovation, Scholarship & Creativity award fro the OSU Research Office to support her summer 2013 research project entitled "Dectection of Fluorescently Labeled Lipoprotein and Determination of Protein Corona Composition on Iron Nanoparticles." Amay will be conducting this project in Dr. Stacey Harper's laboratory.

 

Tanguay Laboratory Paper Receives an Editor's HighlightToxological Science

Dr. Tanguay and his co-authors Lisa Truong, David Reif, Lindsey St. Mary, Mitra  Geier, and Hao Truong have learned that  their recent paper in Toxicological Sciences/"Multidimensional In Vivo Hazard Assessment Using Zebrafish"/  ( Tox Sci 137(1), 212--233, 2014)  received an Editors Highlight: http://toxsci.oxfordjournals.org/content/current (Safety Evaluation).

*Editor's Highlight:*  The Tanguay group uses the embryonic zebrafish model to demonstrate the utility of high throughput screening for toxicology studies. Thegroup evaluated the 1060 US EPA ToxCast Phase 1 and 2 compounds on 18 distinct outcomes. With four doses for each compound the group generated a dizzyingnumber of data points highlighting the importance of bioinformatics analysis in these types of studies. The study shows how it is now possible to screen many ofthe tens of thousands of untested chemicals using a whole animal model in which one can literally see developmental malformations. ---Gary W. Miller, Editor

 *http://toxsci.oxfordjournals.org/content/137/1/212.full.pdf+html*

Tanguay Lab

Joey Pryor Awarded University Honors College Excellence Fund

Joey Pryor was awarded $1,000 from the University Honors College Excellence Fund  to support his research on "Comparative toxicological  assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish" in Dr. Harper's Lab.

Scientists-in-training learn to effectively communicate research to TOX507the public

More than 45 mostly graduate-level students attended the first offering of the course, Communicating Science and Risk Beyond Academia – or TOX 507/607 – this fall to learn to explain their scientific research from experts across Oregon State.

Students in the course discussed communicating to individuals, the public and media through a variety of methods such as blogs, social media and news releases. They learned to revise technical, scientific language to an 8th grade reading level in an effort to reach a broad audience.

“This was one of the more challenging activities,” says Environmental and Molecular Toxicology Assistant Professor Stacey Harper, who helped design the course. “At a minimum, the students gained an appreciation for just how difficult this is.”

 

Staci Simonich Impact AwardStaci Simonich Receives OSU Impact Award for Outstanding Scholarship

The OSU Impact Award for Outstanding Scholarship recognizes OSU faculty who have demonstrated outstanding scholarship in a specific project or activity resulting in substantial impact beyond the university setting. The award consists of identification of the recipient on a plaque prominently displayed in the Research Office, a plaque for the recipient’s college, a plaque for the recipient and a $2,500 honorarium. Staci will also be invited to present the highlights of the work at a one-hour presentation that is open to the public.

To qualify for the Impact Award, an OSU faculty member’s scholarship must be demonstrated by a specific research project or creative activity that was broadly disseminated where the implications of the project or activity were found to have great impact by a broad constituency. Nominations  provided evidence of the impact attending to:

  • A broad dissemination recognizing the specific research project or creative activity and garnering substantial interest by the media and general public.
  • Recognition of a substantial impact by a broad constituency outside OSU of the implications of the research project or creative activity.
  • Completion of the work (e.g., published, presented) within three years of the nomination.

Special Session at ISPAC Honors the Career of Bill Baird

Baird Williams at ISPACDr. Bill Baird (Co-leader, Project 2) was presented with an award in honor of his many years of research, kindness, and mentoring of students. Dr. Dave Williams, SRP Center Director presented it to him.

William McKenzie Baird, PhD, currently Professor, Department of Environmental & Molecular Toxicology and Professor, Department of Biochemistry & Biophysics at Oregon State University  was born in 1944 in Philadelphia PA. He  received his B.S. Chemistry from Lehigh University and his Ph.D. in Oncology from the University  of Wisconsin-Madison. Dr. Baird has previously been appointed as Glenn L. Jenkins  Professor of Medicinal Chemistry and Cancer Center Director at Purdue University, and Director, Environmental Health Sciences Center at Oregon State University.   Dr. Baird has pursued a highly distinguished and internationally recognized career based on developing a molecular understanding of the mechanisms of carcinogenesis by environmental Polycyclic Aromatic Hydrocarbons (PAHs), with an emphasis on the role of metabolism by cytochrome P450 isoforms in activation and detoxification of PAHs;  the interactions of carcinogenic chemicals with nucleic acids and chromatin; chemoprevention and the mechanism of action of chemopreventive agents; and  the role of PAHs  in tumor induction and formation of PAH-DNA adducts as biomarkers for exposure. Dr. Baird has published over 140 peer reviewed manuscripts, been the recipient of continuous major funding from NIH and other extramural research funding agencies and received numerous awards and recognitions. Dr. Baird has  been a leader and mentor in this field for over 40 years,  training students and early career scientists and providing critical new information relating  directly to our understanding the mechanism of action of carcinogenic chemicals to which large numbers of humans are exposed and are important for risk assessment and chemoprevention.

Leah chibwe

Leah Chibwe awarded 2013 KC Donnelly Externship Award

Leah Chibwe, working in Dr. Staci Simonich's laboratory, has received a 2013 KC Donnelly Externship Award from NIEHS to conduct research at the University of North Carolina at Chapel Hill (UNC) with Dr. Michael Aitken.

Leah is from Zambia and completing her second year as a doctoral student in Chemistry. Her research focuses on predicting and measuring the degradation of by-products from polycyclic aromatic hydrocarbons (PAHs) at Superfund sites. This work utilizes state-of-the-art analytical chemistry including Comprehensive 2-Dimensional Gas Chromatography coupled to Time of Flight Mass Spectrometry (GCxGC/ToF-MS).

Madeen/WilliamsErin Madeen wins RSESS Travel Award

Erin Madeen, working in Dr. Dave William's lab, received a Regulatory and Safety Evaluation Specialty Section (RSESS) Travel Award to go to the 2013 annual SOT meeting last March.

The poster she presented was entitled, "In Vivo human pharmacokinetics of dibenzo[def,p]chrysene (DBC) following microdosing. Bridging the gap between high dose animal data and environmentally relevant human exposures".  Erin also won the Diversity Advancement Pipeline Fellowship from the OSU Provost's office

 

 

GoodaleBritton Goodale Receives 2013 Women's Center Student Award

Britton Goodale, working in Robert Tanguay's Lab, received the 2013 Women's Center Student award.

She was recognized for her PAH research contributions and publications. She has taken on leadership roles and is a trusted and dependable student worker in the Tanguay lab.

 

 

Andy LarkinThree Minutes to Change the World

Andy Larkin and Ed O'Donnell recently took part in Schlolars' Insights, a new program of the OSU Graduate School. Master's and doctoral students are asked to condense their research into a presentation no longer than three minutes.

For more information on the presentations, please visit the OSU Graduate School. Andy's presentation is available on YouTube: OSU Scholars Insights 2013 Winners

 

bissonWilliam Bisson Selected for Halifax Project Taskforce and Evaluation International Committee on SLA Italian Research

William Bisson has been selected for the prestigious Evaluation International Committee on SLA Italian research (as an expert in Drug Discovery) and a leader of another international initiative in Cancer initiated in Canada. He will be a leader of one of the taskforces (Biomarker and Disruptive Validation) for a series of peer review papers to be pubished next year. William will lead an international team of scientists in this initiative.

More information on this Halifax Project started by the Getting to Know Cancer Foundation in Canada is available at http://www.gettingtoknowcancer.org/taskforce_environment.php

SRP Student Highlight at NIEHS -Oleksii Motorykin

Oleksii MotorykinOleksii Motorykin, Superfund Research Program (SRP) trainee at Oregon State University, found for the first time that lung cancer deaths are linked to polycyclic aromatic hydrocarbon (PAH) emissions, independent of cigarette smoke. as a result of his hard work and discoveries, Motorkykin received two prestigious awards from the Division of Environmental Chemistry of the American Chemical Society (ACS) in 2013.

Motorykin received a 2013 Graduate Awards in Environmental Chemistry. The ACS Division of Environmental Chemistry sponsors up to 25 annual awards to full-time graduate students based upon students' records in course work, evidence of research productivity, and on statements from graduate faculty advisers.

He also won a 2013 Graduate Student Paper Award for an article about his findings that will soon appear in the journal Environmental Science and Technology. This is the highest award given fy the ACS Division of Environmental Chemistry to its student members.

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