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Recent Department Activities
Tanguay Laboratory Paper Receives an Editor's Highlight
Dr. Tanguay and his co-authors Lisa Truong, David Reif, Lindsey St. Mary, Mitra Geier, and Hao Truong have learned that their recent paper in Toxicological Sciences/"Multidimensional In Vivo Hazard Assessment Using Zebrafish"/ ( Tox Sci 137(1), 212--233, 2014) received an Editors Highlight: http://toxsci.oxfordjournals.org/content/current (Safety Evaluation).
*Editor's Highlight:* The Tanguay group uses the embryonic zebrafish model to demonstrate the utility of high throughput screening for toxicology studies. Thegroup evaluated the 1060 US EPA ToxCast Phase 1 and 2 compounds on 18 distinct outcomes. With four doses for each compound the group generated a dizzyingnumber of data points highlighting the importance of bioinformatics analysis in these types of studies. The study shows how it is now possible to screen many ofthe tens of thousands of untested chemicals using a whole animal model in which one can literally see developmental malformations. ---Gary W. Miller, Editor
Joey Pryor Awarded University Honors College Excellence Fund
Joey Pryor was awarded $1,000 from the University Honors College Excellence Fund to support his research on "Comparative toxicological assessment of PAMAM and thiophosphoryl dendrimers using embryonic zebrafish" in Dr. Harper's Lab.
More than 45 mostly graduate-level students attended the first offering of the course, Communicating Science and Risk Beyond Academia – or TOX 507/607 – this fall to learn to explain their scientific research from experts across Oregon State.
Students in the course discussed communicating to individuals, the public and media through a variety of methods such as blogs, social media and news releases. They learned to revise technical, scientific language to an 8th grade reading level in an effort to reach a broad audience.
“This was one of the more challenging activities,” says Environmental and Molecular Toxicology Assistant Professor Stacey Harper, who helped design the course. “At a minimum, the students gained an appreciation for just how difficult this is.”
Staci Simonich Receives OSU Impact Award for Outstanding Scholarship
The OSU Impact Award for Outstanding Scholarship recognizes OSU faculty who have demonstrated outstanding scholarship in a specific project or activity resulting in substantial impact beyond the university setting. The award consists of identification of the recipient on a plaque prominently displayed in the Research Office, a plaque for the recipient’s college, a plaque for the recipient and a $2,500 honorarium. Staci will also be invited to present the highlights of the work at a one-hour presentation that is open to the public.
To qualify for the Impact Award, an OSU faculty member’s scholarship must be demonstrated by a specific research project or creative activity that was broadly disseminated where the implications of the project or activity were found to have great impact by a broad constituency. Nominations provided evidence of the impact attending to:
- A broad dissemination recognizing the specific research project or creative activity and garnering substantial interest by the media and general public.
- Recognition of a substantial impact by a broad constituency outside OSU of the implications of the research project or creative activity.
- Completion of the work (e.g., published, presented) within three years of the nomination.
Special Session at ISPAC Honors the Career of Bill Baird
Dr. Bill Baird (Co-leader, Project 2) was presented with an award in honor of his many years of research, kindness, and mentoring of students. Dr. Dave Williams, SRP Center Director presented it to him.
William McKenzie Baird, PhD, currently Professor, Department of Environmental & Molecular Toxicology and Professor, Department of Biochemistry & Biophysics at Oregon State University was born in 1944 in Philadelphia PA. He received his B.S. Chemistry from Lehigh University and his Ph.D. in Oncology from the University of Wisconsin-Madison. Dr. Baird has previously been appointed as Glenn L. Jenkins Professor of Medicinal Chemistry and Cancer Center Director at Purdue University, and Director, Environmental Health Sciences Center at Oregon State University. Dr. Baird has pursued a highly distinguished and internationally recognized career based on developing a molecular understanding of the mechanisms of carcinogenesis by environmental Polycyclic Aromatic Hydrocarbons (PAHs), with an emphasis on the role of metabolism by cytochrome P450 isoforms in activation and detoxification of PAHs; the interactions of carcinogenic chemicals with nucleic acids and chromatin; chemoprevention and the mechanism of action of chemopreventive agents; and the role of PAHs in tumor induction and formation of PAH-DNA adducts as biomarkers for exposure. Dr. Baird has published over 140 peer reviewed manuscripts, been the recipient of continuous major funding from NIH and other extramural research funding agencies and received numerous awards and recognitions. Dr. Baird has been a leader and mentor in this field for over 40 years, training students and early career scientists and providing critical new information relating directly to our understanding the mechanism of action of carcinogenic chemicals to which large numbers of humans are exposed and are important for risk assessment and chemoprevention.
Leah Chibwe awarded 2013 KC Donnelly Externship Award
Leah Chibwe, working in Dr. Staci Simonich's laboratory, has received a 2013 KC Donnelly Externship Award from NIEHS to conduct research at the University of North Carolina at Chapel Hill (UNC) with Dr. Michael Aitken.
Leah is from Zambia and completing her second year as a doctoral student in Chemistry. Her research focuses on predicting and measuring the degradation of by-products from polycyclic aromatic hydrocarbons (PAHs) at Superfund sites. This work utilizes state-of-the-art analytical chemistry including Comprehensive 2-Dimensional Gas Chromatography coupled to Time of Flight Mass Spectrometry (GCxGC/ToF-MS).
Erin Madeen wins RSESS Travel Award
Erin Madeen, working in Dr. Dave William's lab, received a Regulatory and Safety Evaluation Specialty Section (RSESS) Travel Award to go to the 2013 annual SOT meeting last March.
The poster she presented was entitled, "In Vivo human pharmacokinetics of dibenzo[def,p]chrysene (DBC) following microdosing. Bridging the gap between high dose animal data and environmentally relevant human exposures". Erin also won the Diversity Advancement Pipeline Fellowship from the OSU Provost's office
Britton Goodale Receives 2013 Women's Center Student Award
Britton Goodale, working in Robert Tanguay's Lab, received the 2013 Women's Center Student award.
She was recognized for her PAH research contributions and publications. She has taken on leadership roles and is a trusted and dependable student worker in the Tanguay lab.
Three Minutes to Change the World
Andy Larkin and Ed O'Donnell recently took part in Schlolars' Insights, a new program of the OSU Graduate School. Master's and doctoral students are asked to condense their research into a presentation no longer than three minutes.
William Bisson Selected for Halifax Project Taskforce and Evaluation International Committee on SLA Italian Research
William Bisson has been selected for the prestigious Evaluation International Committee on SLA Italian research (as an expert in Drug Discovery) and a leader of another international initiative in Cancer initiated in Canada. He will be a leader of one of the taskforces (Biomarker and Disruptive Validation) for a series of peer review papers to be pubished next year. William will lead an international team of scientists in this initiative.
More information on this Halifax Project started by the Getting to Know Cancer Foundation in Canada is available at http://www.gettingtoknowcancer.org/taskforce_environment.php
Oleksii Motorykin, Superfund Research Program (SRP) trainee at Oregon State University, found for the first time that lung cancer deaths are linked to polycyclic aromatic hydrocarbon (PAH) emissions, independent of cigarette smoke. as a result of his hard work and discoveries, Motorkykin received two prestigious awards from the Division of Environmental Chemistry of the American Chemical Society (ACS) in 2013.
Motorykin received a 2013 Graduate Awards in Environmental Chemistry. The ACS Division of Environmental Chemistry sponsors up to 25 annual awards to full-time graduate students based upon students' records in course work, evidence of research productivity, and on statements from graduate faculty advisers.
He also won a 2013 Graduate Student Paper Award for an article about his findings that will soon appear in the journal Environmental Science and Technology. This is the highest award given fy the ACS Division of Environmental Chemistry to its student members.
The Louisiana State University (LSU) and Oregon State University (OSU) Superfund Research Programs (SRP) co-hosted “Response, Recovery, and Resilience to Oil Spills and Environmental Disasters: Engaging Experts and Communities,” a symposium and workshop for community stakeholders, researchers, and policy makers. The purpose of the workshop was to enhance communication between experts and citizens, encouraging better monitoring and sharing of information concerning local environmental conditions following disasters.
Four classes of 8th grade students at Linus Pauling Middle School recently completed a module about oil spills and the subsequent clean-up.
Models take spotlight at council science talks (Environmental Factors - NIEHS News)
Advances in animal models were the focus of two scientific presentations at the Sept. 11 National Advisory Environmental Health Sciences Council meeting. Zebrafish and mice have been model organisms in environmental health sciences for a long time, but today researchers are crafting bold innovations to advance their usefulness as vehicles for scientific inquiry into toxicity and disease.
Council members were treated to exciting, informative talks by NIEHS Superfund Research Program grantee Robert Tanguay, Ph.D., (http://emt.oregonstate.edu/roberttanguay) a distinguished professor of molecular toxicology and head of the Sinnhuber Aquatic Research Laboratory at Oregon State University; and lead researcher Jef French, Ph.D., head of the NTP Host Susceptibility Group within the Biomolecular Screening Branch.
Dr. Stacey Harper has just received a five year, $1.9 million "ONES" award as an 'Outstanding New Environmental Scientist' from the National Institute of Environmental Health Sciences.
Dr. Harper's grant is entitled ‘Integrative Studies to Define Drivers of Nanomaterial Toxicity’ and will focus on elucidating the structural relationships that can predict potential toxicity, understand molecular mechanisms of toxicity, develop safety protocols, and create new, rapid testing strategies and other new tools to help protect both humans and the environment as this new field of nanotoxicology emerges.
This funding opportunity announcement (FOA) targets exceptionally talented early stage investigators who intend to make a long-term career commitment to research in the mission areas of the NIEHS and assist them in launching an innovative research program focusing on problems of environmental exposures and human biology, human pathophysiology and human disease.
The L.L. Stewart Faculty Scholars Program recognizes outstanding faculty at Oregon State University and provides resources to stimulate creative advancements in teaching, research, and extended education. The theme of the award is to support creativity and innovation among the university’s top scholars and is supported by an endowment established by L.L. Stewart. This award provides $30,000 in financial support for faculty selected as a Stewart Scholar. Ten thousand of this amount will be awarded as a stipend to the faculty member, and $20,000 may be used for any allowable teaching, research, or extended education expenses, including faculty release time. During the year after completion of a Stewart Scholar Program, the awardee will deliver the L.L. Stewart Faculty Scholar Lecture. This Lecture (or workshop, if appropriate) will demonstrate or apply the accomplishments of the L.L. Stewart Faculty Scholar Program.
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