David Williams

Professor, Director of Superfund Research Program
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Office: 541-737-3277
Fax: 541-737-0497

Linus Pauling Science Center

Linus Pauling Science Center 473

2900 Southwest Campus Way

2900 Southwest Campus Way
Corvallis, OR 97331

My research interests are in the characterization and regulation of microsomal monooxygenase enzymes (Cytochromes P450 and Flavin-Containing Monooxygenases) active in drug metabolism and their involvement in the detoxication and/or bioactivation of drugs, xenobiotics and endogenous compounds. In addition, a major focus of current research efforts is on diet and cancer.  These studies employ both trout, mouse and human cell culture models to address mechanistic questions.  Currently, we are working on a model that addresses the issue of maternal diet on cancer risk for the fetus in later life.  I am an Investigator in The Linus Pauling Institute and the Marine and Freshwater Biomedical Sciences Center.

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Journal Article