College of Agricultural Sciences

W. M. Baird, “The uses of carcinogen-DNA adduct measurement in establishing mechanisms of mutagenesis and in chemoprevention”, Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, vol. 547, no. 1-2, pp. 1 - 4, 2004.

A. Luch, Coffing, S. L., Tang, Y. M., Schneider, A., Soballa, V., Greim, H., Jefcoate, C. R., Seidel, A., Greenlee, W. F., Baird, W. M., and , “Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo [a, l] pyrene”, Chemical research in toxicology, vol. 11, pp. 686–695, 1998.

B. Mahadevan, Arora, V., Schild, L. J., Keshava, C., Cate, M. L., Iversen, P. L., Poirier, M. C., Weston, A., Pereira, C. B., and Baird, W. M., “Reduction in tamoxifen-induced CYP3A2 expression and DNA adducts using antisense technology”, Molecular Carcinogenesis, vol. 45, no. 2, pp. 118 - 125, 2006.

L. K. Siddens, Larkin, A., Krueger, S. K., Bradfield, C. A., Waters, K. M., Tilton, S. C., Pereira, C. B., öhr, C. V., Arlt, V. M., Phillips, D. H., Williams, D. E., and Baird, W. M., “Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse”, Toxicology and Applied Pharmacology, vol. 264, no. 3, pp. 377 - 386, 2012.

B. Mahadevan, Dashwood, W. - M., Luch, A., Pecaj, A., Doehmer, J., Seidel, A., Pereira, C. B., and Baird, W. M., “Mutations induced by (?)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene in the coding region of the hypoxanthine phosphoribosyltransferase (Hprt) gene in Chinese hamster V79 cells”, Environmental and Molecular Mutagenesis, vol. 41, no. 2, pp. 131 - 139, 2003.

M. K. Lakshman, Kole, P. L., Chaturvedi, S., Saugier, J. H., Yeh, H. J. C., Glusker, J. P., Carrell, H. L., Katz, A. K., Afshar, C. E., Dashwood, W. - M., Kenniston, G., and Baird, W. M., “Methyl Group-Induced Helicity in 1,4-Dimethylbenzo[ c ]phenanthrene and Its Metabolites:  Synthesis, Physical, and Biological Properties”, Journal of the American Chemical Society, vol. 122, no. 51, pp. 12629 - 12636, 2000.

S. C. Tilton, Siddens, L. K., Krueger, S. K., Larkin, A. J., Lohr, C. V., Williams, D. E., Baird, W. M., and Waters, K. M., “Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential”, Toxicological Sciences, vol. 146, no. 1, pp. 135 - 145, 2015.

A. Luch, Kudla, K., Seidel, A., Doehmer, J., Greim, H., and Baird, W. M., “The level of DNA modification by (+)-syn-(11S, 12R, 13S, 14R)-and (–)-anti-(11R, 12S, 13S, 14R)-dihydrodiol epoxides of dibenzo [a, l] pyrene determined the effect on the proteins p53 and p21WAF1 in the human mammary carcinoma cell line MCF-7”, Carcinogenesis, vol. 20, pp. 859–865, 1999.

A. P. Reddy, Harttig, U., Barth, M. C., Baird, W. M., Schimerlik, M., Hendricks, J. D., and Bailey, G. S., “Inhibition of dibenzo [a, l] pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout”, Carcinogenesis, vol. 20, pp. 1919–1926, 1999.

V. J. Melendez-Colon, Luch, A., Seidel, A., and Baird, W. M., “Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures”, Chemical research in toxicology, vol. 13, pp. 10–17, 2000.

V. J. Melendez-Colon, Smith, C. Allen, Seidel, A., Luch, A., Platt, K. L., and Baird, W. M., “Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo [a, l] pyrene or its diol epoxides”, Proceedings of the National Academy of Sciences, vol. 94, pp. 13542–13547, 1997.

B. Mahadevan, Luch, A., Seidel, A., Pelling, J. C., and Baird, W. M., “Effects of the (–)-anti-11R, 12S-dihydrodiol 13S, 14R-epoxide of dibenzo [a, l] pyrene on DNA adduct formation and cell cycle arrest in human diploid fibroblasts”, Carcinogenesis, vol. 22, pp. 161–169, 2001.

C. P. Marston, Pereira, C. B., Ferguson, J., Fischer, K., Hedstrom, O., Dashwood, W. - M., and Baird, W. M., “Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH–DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis”, Carcinogenesis, vol. 22, pp. 1077–1086, 2001.

B. Mahadevan, Luch, A., Bravo, C. F., Atkin, J., Steppan, L. B., Pereira, C. B., Kerkvliet, N. I., and Baird, W. M., “Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo”, Cancer Letters, vol. 227, no. 1, pp. 25 - 32, 2005.

B. Mahadevan, Luch, A., Bravo, C. F., Atkin, J., Steppan, L. B., Pereira, C. B., Kerkvliet, N. I., and Baird, W. M., “Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo.”, Cancer Lett, vol. 227, no. 1, pp. 25-32, 2005.

S. M. Heidel, MacWilliams, P. S., Baird, W. M., W Dashwood, M., Buters, J. T. M., Gonzalez, F. J., Larsen, M. C., Czuprynski, C. J., and Jefcoate, C. R., “Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7, 12-dimethylbenz [a] anthracene”, Cancer research, vol. 60, pp. 3454–3460, 2000.

L. K. Siddens, Bunde, K. L., Harper, T. A., McQuistan, T. J., öhr, C. V., Bramer, L. M., Waters, K. M., Tilton, S. C., Krueger, S. K., Williams, D. E., and Baird, W. M., “Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse”, Toxicology and Applied Pharmacology, vol. 287, no. 2, pp. 149 - 160, 2015.

J. T. M. Buters, Mahadevan, B., Quintanilla-Martinez, L., Gonzalez, F. J., Greim, H., Baird, W. M., and Luch, A., “Cytochrome P450 1B1 Determines Susceptibility to Dibenzo[ a,l ]pyrene-Induced Tumor Formation”, Chemical Research in Toxicology, vol. 15, no. 9, pp. 1127 - 1135, 2002.

V. J. Melendez-Colon, Luch, A., Seidel, A., and Baird, W. M., “Comparison of Cytochrome P450-and Peroxidase-dependent Metabolic Activation of the Potent Carcinogen Dibenzo [a, l] pyrene in Human Cell Lines Formation of Stable DNA Adducts and Absence of a Detectable Increase in Apurinic Sites”, Cancer research, vol. 59, pp. 1412–1416, 1999.

A. Larkin, Siddens, L. K., Krueger, S. K., Tilton, S. C., Waters, K. M., Williams, D. E., and Baird, W. M., “Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin”, Toxicology and Applied Pharmacology, vol. 267, no. 2, pp. 192 - 199, 2013.