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William M Baird
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W. M. Baird
,
“
The uses of carcinogen-DNA adduct measurement in establishing mechanisms of mutagenesis and in chemoprevention
”
,
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
, vol. 547, no. 1-2, pp. 1 - 4, 2004.
S
A. Luch
,
Coffing, S. L.
,
Tang, Y. M.
,
Schneider, A.
,
Soballa, V.
,
Greim, H.
,
Jefcoate, C. R.
,
Seidel, A.
,
Greenlee, W. F.
,
Baird, W. M.
, and
,
“
Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo [a, l] pyrene
”
,
Chemical research in toxicology
, vol. 11, pp. 686–695, 1998.
R
B. Mahadevan
,
Arora, V.
,
Schild, L. J.
,
Keshava, C.
,
Cate, M. L.
,
Iversen, P. L.
,
Poirier, M. C.
,
Weston, A.
,
Pereira, C. B.
, and
Baird, W. M.
,
“
Reduction in tamoxifen-induced CYP3A2 expression and DNA adducts using antisense technology
”
,
Molecular Carcinogenesis
, vol. 45, no. 2, pp. 118 - 125, 2006.
P
L. K. Siddens
,
Larkin, A.
,
Krueger, S. K.
,
Bradfield, C. A.
,
Waters, K. M.
,
Tilton, S. C.
,
Pereira, C. B.
,
öhr, C. V.
,
Arlt, V. M.
,
Phillips, D. H.
,
Williams, D. E.
, and
Baird, W. M.
,
“
Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse
”
,
Toxicology and Applied Pharmacology
, vol. 264, no. 3, pp. 377 - 386, 2012.
M
B. Mahadevan
,
Dashwood, W. - M.
,
Luch, A.
,
Pecaj, A.
,
Doehmer, J.
,
Seidel, A.
,
Pereira, C. B.
, and
Baird, W. M.
,
“
Mutations induced by (?)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene in the coding region of the hypoxanthine phosphoribosyltransferase (Hprt) gene in Chinese hamster V79 cells
”
,
Environmental and Molecular Mutagenesis
, vol. 41, no. 2, pp. 131 - 139, 2003.
M. K. Lakshman
,
Kole, P. L.
,
Chaturvedi, S.
,
Saugier, J. H.
,
Yeh, H. J. C.
,
Glusker, J. P.
,
Carrell, H. L.
,
Katz, A. K.
,
Afshar, C. E.
,
Dashwood, W. - M.
,
Kenniston, G.
, and
Baird, W. M.
,
“
Methyl Group-Induced Helicity in 1,4-Dimethylbenzo[
c
]phenanthrene and Its Metabolites: Synthesis, Physical, and Biological Properties
”
,
Journal of the American Chemical Society
, vol. 122, no. 51, pp. 12629 - 12636, 2000.
S. C. Tilton
,
Siddens, L. K.
,
Krueger, S. K.
,
Larkin, A. J.
,
Lohr, C. V.
,
Williams, D. E.
,
Baird, W. M.
, and
Waters, K. M.
,
“
Mechanism-Based Classification of PAH Mixtures to Predict Carcinogenic Potential
”
,
Toxicological Sciences
, vol. 146, no. 1, pp. 135 - 145, 2015.
L
A. Luch
,
Kudla, K.
,
Seidel, A.
,
Doehmer, J.
,
Greim, H.
, and
Baird, W. M.
,
“
The level of DNA modification by (+)-syn-(11S, 12R, 13S, 14R)-and (–)-anti-(11R, 12S, 13S, 14R)-dihydrodiol epoxides of dibenzo [a, l] pyrene determined the effect on the proteins p53 and p21WAF1 in the human mammary carcinoma cell line MCF-7
”
,
Carcinogenesis
, vol. 20, pp. 859–865, 1999.
I
A. P. Reddy
,
Harttig, U.
,
Barth, M. C.
,
Baird, W. M.
,
Schimerlik, M.
,
Hendricks, J. D.
, and
Bailey, G. S.
,
“
Inhibition of dibenzo [a, l] pyrene-induced multi-organ carcinogenesis by dietary chlorophyllin in rainbow trout
”
,
Carcinogenesis
, vol. 20, pp. 1919–1926, 1999.
F
V. J. Melendez-Colon
,
Luch, A.
,
Seidel, A.
, and
Baird, W. M.
,
“
Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures
”
,
Chemical research in toxicology
, vol. 13, pp. 10–17, 2000.
V. J. Melendez-Colon
,
Smith, C. Allen
,
Seidel, A.
,
Luch, A.
,
Platt, K. L.
, and
Baird, W. M.
,
“
Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo [a, l] pyrene or its diol epoxides
”
,
Proceedings of the National Academy of Sciences
, vol. 94, pp. 13542–13547, 1997.
E
B. Mahadevan
,
Luch, A.
,
Seidel, A.
,
Pelling, J. C.
, and
Baird, W. M.
,
“
Effects of the (–)-anti-11R, 12S-dihydrodiol 13S, 14R-epoxide of dibenzo [a, l] pyrene on DNA adduct formation and cell cycle arrest in human diploid fibroblasts
”
,
Carcinogenesis
, vol. 22, pp. 161–169, 2001.
C. P. Marston
,
Pereira, C. B.
,
Ferguson, J.
,
Fischer, K.
,
Hedstrom, O.
,
Dashwood, W. - M.
, and
Baird, W. M.
,
“
Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH–DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis
”
,
Carcinogenesis
, vol. 22, pp. 1077–1086, 2001.
D
B. Mahadevan
,
Luch, A.
,
Bravo, C. F.
,
Atkin, J.
,
Steppan, L. B.
,
Pereira, C. B.
,
Kerkvliet, N. I.
, and
Baird, W. M.
,
“
Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo
”
,
Cancer Letters
, vol. 227, no. 1, pp. 25 - 32, 2005.
B. Mahadevan
,
Luch, A.
,
Bravo, C. F.
,
Atkin, J.
,
Steppan, L. B.
,
Pereira, C. B.
,
Kerkvliet, N. I.
, and
Baird, W. M.
,
“
Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo.
”
,
Cancer Lett
, vol. 227, no. 1, pp. 25-32, 2005.
C
S. M. Heidel
,
MacWilliams, P. S.
,
Baird, W. M.
,
W Dashwood, M.
,
Buters, J. T. M.
,
Gonzalez, F. J.
,
Larsen, M. C.
,
Czuprynski, C. J.
, and
Jefcoate, C. R.
,
“
Cytochrome P4501B1 mediates induction of bone marrow cytotoxicity and preleukemia cells in mice treated with 7, 12-dimethylbenz [a] anthracene
”
,
Cancer research
, vol. 60, pp. 3454–3460, 2000.
L. K. Siddens
,
Bunde, K. L.
,
Harper, T. A.
,
McQuistan, T. J.
,
öhr, C. V.
,
Bramer, L. M.
,
Waters, K. M.
,
Tilton, S. C.
,
Krueger, S. K.
,
Williams, D. E.
, and
Baird, W. M.
,
“
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse
”
,
Toxicology and Applied Pharmacology
, vol. 287, no. 2, pp. 149 - 160, 2015.
J. T. M. Buters
,
Mahadevan, B.
,
Quintanilla-Martinez, L.
,
Gonzalez, F. J.
,
Greim, H.
,
Baird, W. M.
, and
Luch, A.
,
“
Cytochrome P450 1B1 Determines Susceptibility to Dibenzo[
a,l
]pyrene-Induced Tumor Formation
”
,
Chemical Research in Toxicology
, vol. 15, no. 9, pp. 1127 - 1135, 2002.
V. J. Melendez-Colon
,
Luch, A.
,
Seidel, A.
, and
Baird, W. M.
,
“
Comparison of Cytochrome P450-and Peroxidase-dependent Metabolic Activation of the Potent Carcinogen Dibenzo [a, l] pyrene in Human Cell Lines Formation of Stable DNA Adducts and Absence of a Detectable Increase in Apurinic Sites
”
,
Cancer research
, vol. 59, pp. 1412–1416, 1999.
A
A. Larkin
,
Siddens, L. K.
,
Krueger, S. K.
,
Tilton, S. C.
,
Waters, K. M.
,
Williams, D. E.
, and
Baird, W. M.
,
“
Application of a fuzzy neural network model in predicting polycyclic aromatic hydrocarbon-mediated perturbations of the Cyp1b1 transcriptional regulatory network in mouse skin
”
,
Toxicology and Applied Pharmacology
, vol. 267, no. 2, pp. 192 - 199, 2013.