College of Agricultural Sciences

A. C. Chlebowski, Garcia, G. R., La Du, J. K., Bisson, W. H., Truong, L., SL, M. Simonich, and Tanguay, R. L., “Mechanistic investigations into the developmental toxicity of nitrated and heterocyclic PAHs.”, Toxicol Sci, 2017.

R. Nahta, Al-Mulla, F., Al-Temaimi, R., Amedei, A., Andrade-Vieira, R., Bay, S., Brown, D. G., Calaf, G. M., Castellino, R. C., Cohen-Solal, K. A., and Bisson, W. H., “Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression”, Carcinogenesis, vol. 36, pp. S2–S18, 2015.

A. Sehrawat, Gao, L., Wang, Y., Bankhead, A., McWeeney, S. K., King, C. J., Schwartzman, J., Urrutia, J., Bisson, W. H., Coleman, D. J., Joshi, S. K., Kim, D. - H., Sampson, D. A., Weinmann, S., Kallakury, B. V. S., Berry, D. L., Haque, R., Van Den Eeden, S. K., Sharma, S., Bearss, J., Beer, T. M., Thomas, G. V., Heiser, L. M., and Alumkal, J. J., “LSD1 activates a lethal prostate cancer gene network independently of its demethylase function.”, Proc Natl Acad Sci U S A, 2018.

M. F. Miller, Goodson, W. H., Manjili, M. H., Kleinstreuer, N., Bisson, W. H., and Lowe, L., “Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations.”, Environ Health Perspect, 2017.

B. C. Goodale, La Du, J. K., Tilton, F., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R. L., “Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs”, Toxicological Sciences, vol. 147, no. 2, pp. 397 - 411, 2015.

B. C. Goodale, La Du, J. K., Tilton, S. C., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R., “Ligand-specific transcriptional mechanisms underlie aryl hydrocarbon receptor-mediated developmental toxicity of oxygenated PAHs”, Toxicological Sciences, p. kfv139, 2015.

B. C. Goodale, La Du, J., Tilton, S. C., Sullivan, C. M., Bisson, W. H., Waters, K. M., and Tanguay, R. L., “Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.”, Toxicol Sci, vol. 147, no. 2, pp. 397-411, 2015.

W. H. Bisson, Scapozza, L., Westera, G., Mu, L., and Schubiger, P. A., “Ligand selectivity for the acetylcholine binding site of the rat $\alpha$4$\beta$2 and $\alpha$3$\beta$4 nicotinic subtypes investigated by molecular docking”, Journal of medicinal chemistry, vol. 48, pp. 5123–5130, 2005.

J. - I. Lee, Nian, H., Cooper, A. J. L., Sinha, R., Dai, J., Bisson, W. H., Dashwood, R. H., and Pinto, J. T., “ -Keto Acid Metabolites of Naturally Occurring Organoselenium Compounds as Inhibitors of Histone Deacetylase in Human Prostate Cancer Cells”, Cancer Prevention Research, vol. 2, no. 7, pp. 683 - 693, 2009.

C. Jiang, Xie, C., Lv, Y., Li, J., Krausz, K. W., Shi, J., Brocker, C. N., Desai, D., Amin, S. G., Bisson, W. H., Liu, Y., Gavrilova, O., Patterson, A. D., and Gonzalez, F. J., “Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction”, Nature Communications, vol. 6, p. 10166, 2015.

F. J. Gonzalez, Jiang, C., Bisson, W. H., and Patterson, A. D., “Inhibition of farnesoid X receptor signaling shows beneficial effects in human obesity”, Journal of hepatology, 2015.

J. Ochieng, Nangami, G. N., Ogunkua, O., Miousse, I. R., Koturbash, I., Odero-Marah, V., McCawley, L., Nangia-Makker, P., Ahmed, N., Luqmani, Y., and Bisson, W. H., “The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis”, Carcinogenesis, vol. 36, pp. S128–S159, 2015.

H. Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B., Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells”, Biology (Basel), vol. 6, no. 4, 2017.

H. Sang Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B. Duc, Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., “Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells.”, Biology (Basel), vol. 6, no. 4, 2017.

K. J. Smith, Murray, I. A., Tanos, R., Tellew, J., Boitano, A. E., Bisson, W. H., Kolluri, S., Cooke, M. P., and Perdew, G. H., “Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism”, Journal of Pharmacology and Experimental Therapeutics, vol. 338, pp. 318–327, 2011.

W. H. Bisson, Westera, G., P Schubiger, A., and Scapozza, L., “Homology modeling and dynamics of the extracellular domain of rat and human neuronal nicotinic acetylcholine receptor subtypes $\alpha$4$\beta$2 and $\alpha$7”, Journal of molecular modeling, vol. 14, pp. 891–899, 2008.

E. Kim, Bisson, W. H., Löhr, C. V., Williams, D. E., Ho, E., Dashwood, R. H., and Rajendran, P., “Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors.”, Curr Top Med Chem, vol. 16, no. 7, pp. 714-31, 2016.

Y. Kang, Nian, H., Rajendran, P., Kim, E., Dashwood, W. M., Pinto, J. T., Boardman, L. A., Thibodeau, S. N., Limburg, P. J., Löhr, C. V., and Bisson, W. H., “HDAC8 and STAT3 repress BMF gene activity in colon cancer cells”, Cell death & disease, vol. 5, p. e1476, 2014.

P. Rajendran, Kidane, A. I., Yu, T. - W., Dashwood, W. - M., Bisson, W. H., Löhr, C. V., Ho, E., Williams, D. E., and Dashwood, R. H., “HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates”, Epigenetics, vol. 8, pp. 612–623, 2013.

L. Sun, Xie, C., Wang, G., Wu, Y., Wu, Q., Wang, X., Liu, J., Deng, Y., Xia, J., Chen, B., Zhang, S., Yun, C., Lian, G., Zhang, X., Zhang, H., Bisson, W. H., Shi, J., Gao, X., Ge, P., Liu, C., Krausz, K. W., Nichols, R. G., Cai, J., Rimal, B., Patterson, A. D., Wang, X., Gonzalez, F. J., and Jiang, C., “Gut microbiota and intestinal FXR mediate the clinical benefits of metformin.”, Nat Med, 2018.

M. Crisma, Bisson, W. H., Formaggio, F., Broxterman, Q. B., and Toniolo, C., “Factors governing 310-helix vs $\alpha$-helix formation in peptides: Percentage of C$\alpha$-tetrasubstituted $\alpha$-amino acid residues and sequence dependence”, Biopolymers, vol. 64, pp. 236–245, 2002.

B. C. Brinchmann, Le Ferrec, E., Bisson, W. H., Podechard, N., Huitfeldt, H. S., Gallais, I., Sergent, O., Holme, ørnA., Lagadic-Gossmann, D., and Øvrevik, J., “Evidence of selective activation of aryl hydrocarbon receptor nongenomic calcium signaling by pyrene”, Biochemical Pharmacology, vol. 158, pp. 1 - 12, 2018.

A. D. Benninghoff, Bisson, W. H., Koch, D. C., Ehresman, D. J., Kolluri, S., and Williams, D. E., “Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro”, Toxicological sciences, p. kfq379, 2010.

W. H. Bisson, “Environmental immune disruptors, inflammation and carcinogenesis: A state of the science and new horizons”, Toxicology Letters, vol. 280, pp. S9 - S10, 2017.

P. A. Thompson, Khatami, M., Baglole, C. J., Sun, J., Harris, S. A., Moon, E. - Y., Al-Mulla, F., Al-Temaimi, R., Brown, D. G., Colacci, A. Maria, and Bisson, W. H., “Environmental immune disruptors, inflammation and cancer risk”, Carcinogenesis, vol. 36, pp. S232–S253, 2015.