Found 32 results
Author Title [ Type(Desc)] Year
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Journal Article
C. E. Ruby, Leid, M., and Kerkvliet, N. I., 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin suppresses tumor necrosis Factor-$\alpha$ and Anti-CD40–Induced Activation of NF-$ąppa$B/Rel in dendritic cells: p50 Homodimer Activation is not affected, Molecular pharmacology, vol. 62, pp. 722–728, 2002.
B. A. Vorderstrasse and Kerkvliet, N. I., 2,3,7,8-Tetrachlorodibenzo-p-dioxin Affects the Number and Function of Murine Splenic Dendritic Cells and Their Expression of Accessory Molecules, Toxicology and Applied Pharmacology, vol. 171, no. 2, pp. 117 - 125, 2001.
A. K. Ehrlich, Pennington, J. M., Wang, X., Rohlman, D., Punj, S., Löhr, C. V., Newman, M. T., Kolluri, S., and Kerkvliet, N. I., Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice., J Immunol, vol. 196, no. 1, pp. 264-73, 2016.
C. J. Funatake, Marshall, N. B., and Kerkvliet, N. I., Advertisement In utero Exposure of Mice to Dibenzo[a,l]Pyrene Produces Lymphoma in the Offspring: Role of the Aryl Hydrocarbon Receptor , Journal of Immunotoxicology, vol. 5, no. 1, pp. 81 - 91, 2008.
A. K. Ehrlich, Pennington, J. M., Tilton, S., Wang, X., Marshall, N. B., Rohlman, D., Funatake, C., Punj, S., O'Donnell, E. F., Yu, Z., Kolluri, S., and Kerkvliet, N. I., AhR activation increases IL-2 production by alloreactive CD4 T cells initiating the differentiation of mucosal-homing Tim3 Lag3 Tr1 cells., Eur J Immunol, vol. 47, no. 11, pp. 1989-2001, 2017.
D. C. Koch, Jang, H. S., O'Donnell, E. F., Punj, S., Kopparapu, P. R., Bisson, W. H., Kerkvliet, N. I., and Kolluri, S., Anti-androgen flutamide suppresses hepatocellular carcinoma cell proliferation via the aryl hydrocarbon receptor mediated induction of transforming growth factor-β1., Oncogene, 2015.
D. M. Shepherd, Steppan, L. B., Hedstrom, O. R., and Kerkvliet, N. I., Anti-CD40 Treatment of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-Exposed C57Bl/6 Mice Induces Activation of Antigen Presenting Cells Yet Fails to Overcome TCDD-Induced Suppression of Allograft Immunity, Toxicology and Applied Pharmacology, vol. 170, no. 1, pp. 10 - 22, 2001.
E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R., and , The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor, PLoS One, vol. 5, p. e13128, 2010.
E. F. O'Donnell, Saili, K. S., Koch, D. C., Kopparapu, P. R., Farrer, D., Bisson, W. H., Mathew, L. K., Sengupta, S., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S. Kumar, The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor., PLoS One, vol. 5, no. 10, 2010.
E. F. O'Donnell, Jang, H. Sang, Pearce, M. C., Kerkvliet, N. I., and Kolluri, S., The aryl hydrocarbon receptor is required for induction of p21cip1/waf1 expression and growth inhibition by SU5416 in hepatoma cells., Oncotarget, vol. 8, no. 15, pp. 25211-25225, 2017.
E. F. O'Donnell, Kopparapu, P. Rao, Koch, D. C., Jang, H. Sang, Phillips, J. Lynne, Tanguay, R. L., Kerkvliet, N. I., and Kolluri, S. Kumar, The aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells., PLoS One, vol. 7, no. 7, p. e40926, 2012.
B. A. Vorderstrasse, Steppan, L. B., Silverstone, A. E., and Kerkvliet, N. I., Aryl Hydrocarbon Receptor-Deficient Mice Generate Normal Immune Responses to Model Antigens and Are Resistant to TCDD-Induced Immune Suppression, Toxicology and Applied Pharmacology, vol. 171, no. 3, pp. 157 - 164, 2001.
S. Punj, Kopparapu, P., Jang, H. Sang, Phillips, J. Lynne, Pennington, J. M., Rohlman, D., O'Donnell, E. F., Iversen, P. L., Kolluri, S., and Kerkvliet, N. I., Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease., PLoS One, vol. 9, no. 2, p. e88726, 2014.
J. R. Maxwell, Ruby, C., Kerkvliet, N. I., and Vella, A. T., Contrasting the roles of costimulation and the natural adjuvant lipopolysaccharide during the induction of T cell immunity, The Journal of Immunology, vol. 168, pp. 4372–4381, 2002.
R. A. Prell, Dearstyne, E., Steppan, L. G., Vella, A. T., and Kerkvliet, N. I., CTL Hyporesponsiveness Induced by 2,3,7,8-Tetrachlorodibenzo-p-dioxin: Role of Cytokines and Apoptosis, Toxicology and Applied Pharmacology, vol. 166, no. 3, pp. 214 - 221, 2000.
C. J. Funatake, Marshall, N. B., Steppan, L. B., Mourich, D. V., and Kerkvliet, N. I., Cutting edge: activation of the aryl hydrocarbon receptor by 2,3,7,8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of regulatory T cells., J Immunol, vol. 175, no. 7, pp. 4184-8, 2005.
B. Mahadevan, Luch, A., Bravo, C. F., Atkin, J., Steppan, L. B., Pereira, C. B., Kerkvliet, N. I., and Baird, W. M., Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo., Cancer Lett, vol. 227, no. 1, pp. 25-32, 2005.
B. Mahadevan, Luch, A., Bravo, C. F., Atkin, J., Steppan, L. B., Pereira, C. B., Kerkvliet, N. I., and Baird, W. M., Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo, Cancer Letters, vol. 227, no. 1, pp. 25 - 32, 2005.
C. J. Funatake and Kerkvliet, N. I., Early Consequences of 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure on the Activation and Survival of Antigen-Specific T Cells, Toxicological Sciences, vol. 82, no. 1, pp. 129 - 142, 2004.
J. - Y. Choi, Oughton, J. A., and Kerkvliet, N. I., Functional alterations in CD11b(+)Gr-1(+) cells in mice injected with allogeneic tumor cells and treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin., Int Immunopharmacol, vol. 3, no. 4, pp. 553-70, 2003.
H. Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B., Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells, Biology (Basel), vol. 6, no. 4, 2017.
H. Sang Jang, Pearce, M. C., O'Donnell, E. F., Nguyen, B. Duc, Truong, L., Mueller, M. J., Bisson, W. H., Kerkvliet, N. I., Tanguay, R. L., and Kolluri, S., Identification of a Raloxifene Analog That Promotes AhR-Mediated Apoptosis in Cancer Cells., Biology (Basel), vol. 6, no. 4, 2017.
B. A. Vorderstrasse and Kerkvliet, N. I., Influence of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on the Antigen-Presenting Activity of Dendritic Cells, Toxicological Sciences, vol. 72, no. 1, pp. 103 - 112, 2003.
E. A. Dearstyne and Kerkvliet, N. I., Mechanism of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-induced decrease in anti-CD3-activated CD4+ T cells: the roles of apoptosis, Fas, and TNF, Toxicology, vol. 170, pp. 139–151, 2002.
W. H. Bisson, Koch, D. C., Donnell, E. F. ’, Khalil, S. M., Kerkvliet, N. I., Tanguay, R. L., Abagyan, R., and Kolluri, S., Modeling of the Aryl Hydrocarbon Receptor (AhR) Ligand Binding Domain and Its Utility in Virtual Ligand Screening to Predict New AhR Ligands, Journal of Medicinal Chemistry, vol. 52, no. 18, pp. 5635 - 5641, 2009.

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