TitleZebrafish: A marvel of high-throughput biology for 21 century toxicology.
Publication TypeJournal Article
Year of Publication2014
AuthorsBugel, SM, Tanguay, RL, Planchart, A
JournalCurr Environ Health Rep
Volume1
Issue4
Pagination341-352
Date Published2014 Sep 07
ISSN2196-5412
Abstract

The evolutionary conservation of genomic, biochemical and developmental features between zebrafish and humans is gradually coming into focus with the end result that the zebrafish embryo model has emerged as a powerful tool for uncovering the effects of environmental exposures on a multitude of biological processes with direct relevance to human health. In this review, we highlight advances in automation, high-throughput (HT) screening, and analysis that leverage the power of the zebrafish embryo model for unparalleled advances in our understanding of how chemicals in our environment affect our health and wellbeing.

DOI10.1007/s40572-014-0029-5
Alternate JournalCurr Environ Health Rep
PubMed ID25678986
PubMed Central IDPMC4321749
Grant ListP30 ES000210 / ES / NIEHS NIH HHS / United States
R01 ES016896 / ES / NIEHS NIH HHS / United States
T32 ES007060 / ES / NIEHS NIH HHS / United States