Dept: EMT (1007 Ag and Life Sciences Bldg)
Dr. Marcus is an expert in the structure, function and expression of the cytochromes P450 super family of enzymes. His laboratory studies these proteins with a current focus on the role of these enzymes in the metabolism of various important endogenous signaling molecules as well as human therapeutic drugs. These endogenous chemical entities are hypothesized to play important roles in cell growth and differentiation, and hence function as key mediators in the
development and progress of several diseases (glaucoma and
cardiovascular disease) and cancers (breast and prostate). The long term goals of this research are focused on developing improved
diagnostic markers as well as prevention and treatment interventions for human diseases, and better understanding of the pharmacogenomics for human drug metabolism and drug:drug interactions.
Dr. Marcus is also an Internal Advisor for part of the Superfund Research Project's Administrator Core A.